Key publications

Perić-Hassler L, Stjernschantz E, Oostenbrink C, Geerke DP. CYP 2D6 binding affinity predictions using multiple ligand and protein conformations. Int J Mol Sci. 2013 Dec 17;14(12):24514-30. doi: 10.3390/ijms141224514.

Dragovic S, Boerma JS, Vermeulen NP, Commandeur JN. Effect of human glutathione S-transferases on glutathione-dependent inactivation of cytochrome P450-dependent reactive intermediates of diclofenac. Chem Res Toxicol. 2013 Nov 18;26(11):1632-41. doi: 10.1021/tx400204d. Epub 2013 Nov 5.

van Leeuwen JS, Vermeulen NP, Chris Vos J. Yeast as a humanized model organism for biotransformation-related toxicity. Curr Drug Metab. 2012 Dec;13(10):1464-75.