A decade after the unraveling of the human genome a wealth of biological data has become available. This data explosion offers chemistry-related disciplines huge opportunities to convert this knowledge into relevant benefits for society. This can be accomplished by e.g. translating biological understanding into effective medicines and biomarkers.
With its high interdisciplinary nature, the Medicinal Chemistry research group acts on the interface of biology and chemistry, combining fundamental expertise in synthetic organic chemistry, computational chemistry, cheminformatics, biochemistry and structural biology.
The mission of this research group is to understand ligand-protein interaction at the molecular detail, and to use this knowledge for the computational design and synthesis of new bioactive molecules. With these core activities, the Medicinal Chemistry research group aims to be a pivotal player in interdisciplinary scientific networks with a focus on two complementary theme’s:
- G-protein coupled receptors
- Fragment-based drug design