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FAME:modeling made easy

02-09-12

To facilitate systems biologists in their efforts to build genome-scale metabolic models, Joost Boele, Brett Olivier and Bas Teusink (VU Amsterdam) offer FAME - the Flux Analysis and Modeling Environment.

VU Analytical Chemists bring SPRing

01-22-12

Researchers from the Division of BioMolecular Analysis of VU University Amsterdam together with colleagues from Wageningen University (WU) obtained a grant to develop enhanced bioresolution and miniaturization of Surface Plasmon Resonance optical sensing ‘SPRing’.

In silico hit hunters: virtual reality in drug discovery

01-09-12

Computational medicinal chemists Albert Kooistra and Chris de Graaf set a new world record virtual screening for the identification of novel pharmaceutical drugs

Enade Istyastono (Medicinal Chemistry, VU University Amsterdam) wins Henk Timmerman award for computational medicinal chemistry research

11-22-11

Enade Istyastono, PhD-student in the Division of Medicinal Chemistry, obtained a prestigious Henk Timmerman Award, honoring outstanding young Indonesian researchers who are working in the area of pharmaceutical sciences.

Pharmacological tool developed by VU Medicinal Chemists to study inflammation

11-03-11

VUF8430 is a selective agonist of the histamine H4 receptor that has been discovered and pharmacologically characterized by Rogier Smits and Herman Lim during their PhD projects in the Medicinal Chemistry Division of the VU. Recently VUF8430 has been included in the chemical catalogues of Ovata Chemicals and Tocris Bioscience, making this pharmacological tool generally available to the study of H4R-mediated inflammation.

NWO-VENI for Filipe Santos

10-18-11

Dr. F. (Filipe) Branco dos Santos of the group of Systems Bioinformatics received a VENI grant

Honorary Doctorate for Nico Vermeulen

10-18-11

During the celebration on 18 November 2011 the University of Copenhagen will appoint Professor Nico P.E. Vermeulen as honorary doctor associated with the Pharmaceutical Sciences.

iGEM team Amsterdam wins golden medal

10-11-11

iGEM team Amsterdam wins golden medal

Therapeutic nanobody discovered by VU Medicinal Chemists enters clinical trials

10-01-11

Researchers from the Division Medicinal Chemistry (led by Prof. Martine Smit and Prof. Rob Leurs) and the Belgian Biotech company Ablynx have discovered the first llama-derived single chain antibody (nanobody) targeting the CXCR4 chemokine receptor, a protein that plays a key regulatory role in hematopoietic stem cell trafficking. Ablynx has developed and initiated a Phase I clinical trial in healthy volunteers with the therapeutic nanobody ALX-0651, for use in stem cell mobilisation. ALX-0651 is the first Nanobody in clinical trials targeting a GPCR, a target class that has proven to be difficult to address with conventional antibodies.

AIMMS Post-Graduate School Chemical Biology successful

09-22-11

The first course of the AIMMS Post-Graduate School has been a great success

Seven new AIMMS PhD projects!!!

09-01-11

AIMMS initiates seven PhD projects to stimulate the collaboration between members of the institute from the different faculties. After a selection procedure including a review by external reviewers seven proposals have been granted and from this moment on, the projects can start!

Two events in Synthetic Biology at the VU.

08-17-11

iGEM Jamboree Europe and “Meeting of Young Minds” at the VU

Nico Vermeulen in Nature Reviews Drug Discovery

08-04-11

Adverse Drug Reactions (ADRs) are a major complication of drug therapy and an impediment to drug development and clinical use after marketing. Chemically reactive metabolites (CRMs) constitute a major cause of ADRs. Nico Vermeulen (Division of Molecular Toxicology) and a number of other experts in the field have evaluated the current strategies to manage the challenge of chemically reactive metabolites (CRMs) in drug development and proposed new insights and practices to be considered by academia and industry

Dr. Iwan de Esch (VU Medicinal Chemistry) wins Galenus Researchprize for Biocomputational Molecular Design & Chemical Synthesis

06-29-11

Dr. Iwan de Esch, Associate Professor in the Medicinal Chemistry group at VU University Amsterdam has received the prestigious Galenus Research Prize. The prize (5.500 Euros and a golden medal) was awarded on Monday June 27th in the presence of minister Schippers.

AIMMS researchers successful

05-02-11

Joen Luirink, Henry Vischer, Rob Leurs, BasTeusink and Martine Smit scored grants at EU-KP7, NWO, STW and NGI-Zenith

 
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